Tus thrombin (prothrombin) noob nyob rau ntawm kaum ib chromosome (11p11-q12).
Puas thrombin pom hauv plasma?
Cov glycoprotein prothrombin, uas tshwm sim hauv ntshav ntshav, hloov mus rau hauv thrombin los ntawm qhov ua kom ntshav txhaws hu ua factor X lossis prothrombinase; thrombin ces ua rau hloov fibrinogen, kuj muaj nyob rau hauv plasma, ua fibrin, uas, ua ke nrog platelets los ntawm cov ntshav, tsim cov ntshav txhaws. …
tib neeg thrombin tuaj qhov twg?
Thrombin yog ib tug tswv cuab ntawm serine protease tsev neeg, thiab nws yog generated los ntawm nws inactive precursor prothrombin los ntawm Factor Xa, raws li ib feem ntawm lub prothrombinase complex, nyob rau saum npoo ntawm activated cells. Cov tshuaj tiv thaiv hemostatic yog qhov paub zoo tshaj plaws ntawm thrombin.
Pom tau fibrin nyob qhov twg?
Fibrin, ib qho protein uas tsis txaus ntseeg uas tsim tawm los ntawm kev los ntshav thiab yog cov khoom tseem ceeb ntawm cov ntshav txhaws. Fibrin yog ib qho tawv nqaij protein uas tau teem rau hauv cov hlua ntev ntev; Nws yog tsim los ntawm fibrinogen, ib tug soluble protein uas yog tsim los ntawm lub siab thiab pom nyob rau hauv cov ntshav plasma
Yuav ua li cas thrombin tsim?
Thrombin yog tsim los ntawm cov txheej txheem nyuaj ntawm cov txheej txheem proteolytic uas yog pib thaum cov ntaub so ntswg cryptic cuam tshuam nrog cov ntshav plasma VIIa los pib cov txheej xwm nyuaj ua rau tsim cov Cov ntshav coagulation enzyme complexes uas ua rau kom muaj txiaj ntsig ntawm cov enzyme.