Lub neej ntev ib nrab ntawm amiodarone (kwv yees li 50 hnub) yuav ua rau muaj kev cuam tshuam qeeb ntawm cov teebmeem tshwm sim tom qab tso tseg cov tshuaj 4.
Dab tsi yog ib nrab-lub neej ntawm amiodarone Vim li cas qhov no tseem ceeb kom paub?
Kev Ua Phem Txhaum Cai
Vim qhov ntev ib nrab ntawm lub neej ntawm Amiodarone ( 15 txog 142 hnub) thiab nws cov metabolite desethylAmiodarone (14 mus rau 75 hnub), kev phiv tshuaj thiab kev sib cuam tshuam tshuaj tuaj yeem tshwm sim tau ob peb lub lis piam tom qab Amiodarone txiav tawm [saib Clinical Pharmacology (12.3)].
Ib nrab-lub neej ntawm amiodarone IV yog dab tsi?
Amiodarone pharmacokinetics ua kom pom qhov sib txawv ntawm cov neeg mob sib txawv thiab muaj cov yam ntxwv ntawm cov ntaub so ntswg nthuav dav (lub xeev ntim ntawm kev faib tawm 40-84 L / kg), qeeb tag nrho lub cev tshem tawm (90-158 mL / h / kg), lub sijhawm ntev Kev tshem tawm ib nrab-lub neej (20-47 d), thiab ntau cov metabolism hauv siab.
Kev tshem tawm ib nrab-lub neej ntawm amiodarone yog dab tsi?
Tom qab kev kho qhov ncauj mus ntev, amiodarone muaj qhov tseeb tshem tawm ib nrab-lub neej ntawm 60 thiab 142 hnub [2, 3].
Koj yuav tsum saib xyuas dab tsi thaum tus neeg mob siv amiodarone?
Cov neeg mob kho nrog amiodarone yuav tsum tau ua raws li niaj zaus los ntsuas txuas ntxiv xav tau amiodarone, kev ua tau zoo ntawm cov tshuaj, qhov tsim nyog ntawm ntau npaum li cas, kev tsis zoo, thiab kev sib cuam tshuam ntawm cov tshuaj.
