Aberrations uas ua rau anaphase txuas hniav tuaj yeem tiv thaiv cytokinesis. yog nyob rau hauv cov kev tshawb fawb ntawm cov hlwb nyob rau hauv cov ntaub so ntswg kab lis kev cai, rau cov cell yog loj hlob nyob rau hauv ncaj qha xov xwm thiab muaj peev xwm sawv ib tug loj npaum li cas ntawm polyploidy thiab aneu-ploidy. siv nyob rau hauv cov hnub thaum ntxov ntawm radiotherapy.
Yuav ua li cas thiaj ua rau lub voj voog ntawm tes ua rau qog tsim?
mob qog noj ntshav tsis tau kuaj xyuas kev loj hlob ntawm tes. Kev hloov pauv hauv cov noob tuaj yeem ua rau mob qog noj ntshav los ntawm nrawm nrawm ntawm cell faib cov nqi lossis inhibiting ib txwm tswj ntawm lub cev, xws li lub voj voog kaw ntawm tes lossis programmed cell tuag. Raws li qhov loj ntawm cov qog nqaij hlav loj hlob tuaj, nws tuaj yeem loj hlob mus rau hauv cov qog.
Dab tsi yog aberration hauv cell cycle?
Chromosomal aberrations feem ntau yog soj ntsuam hauv thawj metaphases (M1) tom qab raug chromosome-breaking agents Thaum lub sij hawm tom ntej ntawm tes muaj kev xaiv zoo tiv thaiv cov hlwb aberrant. … Hauv M1 hlwb, chromatid-hom aberrations, xws li chromatid so thiab chromatid translocations tshwm sim.
Yuav ua li cas yuam kev hauv lub voj voog ntawm tes ua rau muaj kab mob?
Kev ua yuam kev thaum lub sij hawm mitosis ua rau cov ntxhais cov hlwb nrog ntau dhau los yog tsawg tus chromosomes, ib qho uas hu ua aneuploidy. Yuav luag tag nrho cov aneuploidies uas tshwm sim los ntawm kev ua yuam kev hauv meiosis los yog thaum ntxov embryonic txoj kev loj hlob yog tuag, nrog rau qhov tseem ceeb tshwj xeeb ntawm trisomy 21 nyob rau hauv tib neeg.
Yuav ua li cas chromosomal txawv txav ua rau mob qog noj ntshav?
Chromosomal rearrangements tuaj yeem ua rau mob qog noj ntshav los ntawm kev tsim cov noob hybrid lossis los ntawm kev ua kom tsis zoo ntawm cov noob. Nco qab zaj dab neeg ntawm Philadelphia chromosome, uas yog tsim los ntawm ib tug rearrangement uas tsim cov hybrid bcr-abl noob.
