Bupivacaine yog qhov mob plawv tshaj plaws ntawm LAs (Table 3.10), cov teebmeem cardiotoxic tau txhim kho los ntawm hypoxia, hypercapnia, acidosis thiab hyperkalemia.
Qhov tshuaj loog hauv zos twg yog qhov tsawg tshaj plaws cardiotoxic?
Tus S(−) enantiomer ntawm bupivacaine tau pom tias muaj zog ntau dua 3 thiab tsawg dua cardiotoxic dua R(+) enantiomer4 ua rau kev xaiv ntawm S(−) enantiomer, levobupivacaine, ua lwm txoj hauv kev nyab xeeb rau bupivacaine. Ob qho tshuaj muaj kev lag luam zoo dua li bupivacaine raws li kev tshawb fawb tsiaj.
Puas yog bupivacaine ntau cardiotoxic dua bupivacaine?
Kev kuaj mob ntawm LA Systemic Toxicity
Cov tshuaj loog hauv zos feem ntau tsim cov cim thiab cov tsos mob zoo sib xws, txawm hais tias qhov piv ntawm neurotoxicity: cardiotoxicity yuav txawv ntau (nrog bupivacaine yog qhov feem ntau cardiotoxicity.).
Qhov tshuaj loog hauv zos twg yog qhov nyab xeeb tshaj?
Novocaine yog tshuaj loog hauv zos nyab xeeb thiab siv tau zoo. Nws yog feem ntau siv hauv kev kho hniav rau cov txheej txheem uas siv sijhawm tsawg dua 90 feeb los ua. Ntau yam cuam tshuam rau lub sijhawm Novocaine kav ntev, suav nrog koob tshuaj thiab kev siv tshuaj epinephrine.
bupivacaine cuam tshuam rau lub siab li cas?
Bupivacaine ua rau kev ntxhov siab cuam tshuam txog kev nyuaj siab ntawm intra-atrial, A-V nodal, intraventricular conduction thiab myocardial contractility vim muaj cov sodium ceev ceev thaiv hauv cov hlab ntsha thiab cov hlab plawv.
