Glutamate yog tib cov amino acid nyob rau hauv cov ntaub so ntswg mammalian undergoing oxidative deamination ntawm tus nqi txaus siab. Cov tshuaj tiv thaiv no siv cov nicotinamide adenine dinucleotide (NAD+), los yog nws cov phosphorylated derivative (NADP+) ua tus neeg sawv cev oxidizing, tsim cov ntaub ntawv txo. cov cofactors, NADH lossis NADPH.
Dab tsi yog amino acids deaminated tsim nyob rau hauv daim siab?
Cov α-amino pawg ntawm ntau cov amino acids raug xa mus rau α-ketoglutarate los ua glutamate, uas yog tom qab ntawd oxidatively deaminated kom tawm los ammonium ion (NH 4 +).
Cov amino acids twg tuaj yeem deaminated?
Peb cov amino acids tuaj yeem deaminated ncaj qha: glutamate (catalysed los ntawm glutamate dehydrogenase), glycine (catalysed los ntawm glycine oxidase) thiab serine (catalysed los ntawm serine dehydrogenase).
Cov amino acids twg yog metabolized hauv daim siab?
Lub siab ua lub luag haujlwm tseem ceeb hauv cov amino acid (AA) metabolism hauv tib neeg thiab lwm yam tsiaj. Nyob rau hauv tag nrho cov tsiaj, lub cev no synthesizes ntau AAs (xws li glutamate, glutamine, alanine, aspartate, asparagine, glycine, serine, thiab homoarginine), qabzib, thiab glutathione (ib tug loj antioxidant).
Dab tsi yog deamination hauv siab?
Deamination yog kev tshem tawm ntawm pawg amino los ntawm cov molecule Enzymes uas catalyze cov tshuaj tiv thaiv no hu ua deaminases. Hauv tib neeg lub cev, deamination tshwm sim feem ntau hauv daim siab, txawm li cas los xij nws tuaj yeem tshwm sim hauv lub raum. … Cov amino pawg raug tshem tawm ntawm cov amino acid thiab hloov mus rau ammonia.
