Hauv tsiaj, cov amino acids leucine thiab isoleucine, nrog rau cov fatty acids, tsis tuaj yeem siv los tsim cov piam thaj vim lawv hloov ua ntej rau acetyl-CoA, thiab tsiaj muaj Tsis muaj txoj hauv kev rau acetyl-CoA rau oxaloacetate conversion.
YYuav siv leucine rau gluconeogenesis?
Qhov no tsis yog tib txoj hauv kev rau Acetyl-CoA. Acetyl-CoA tuaj yeem los ntawm carbs, rog, lossis proteins. … Yog li tej zaum koj yuav xav tias – huag txias, koj tau acetyl-CoA los ntawm leucine, yog li koj tuaj yeem siv leucine los ua acetyl-CoA los ua oxaloacetate (OAA) thiab shuttle uas OAA tawm los ua cov piam thaj los ntawm gluconeogenesis.
Dab tsi tsis tuaj yeem yog substrate rau gluconeogenesis?
Gluconeogenesis tsis suav nrog kev hloov pauv ntawm fructose lossis galactose rau cov piam thaj hauv lub siab lossis tsim cov piam thaj los ntawm glycogen ntawm glycogenolysis. … Cov substrates loj rau gluconeogenesis yog lactate, pyruvate, propionate, glycerol, thiab 18 ntawm 20 amino acids (qhov kev zam yog leucine thiab lysine).
Vim li cas acetyl-CoA tsis suav tias yog lub substrate rau gluconeogenesis?
Fatty acids thiab ketogenic amino acids tsis tuaj yeem siv los ua ke cov piam thaj. Cov tshuaj tiv thaiv kev hloov pauv yog ib txoj kev tshuaj tiv thaiv, txhais tau tias acetyl-CoA tsis tuaj yeem hloov rov qab rau pyruvate. Yog li ntawd, fatty acids tsis tuaj yeem siv los tsim cov piam thaj, vim tias beta-oxidation tsim acetyl-CoA.
YPuas amino acids muab substrates rau gluconeogenesis?
Gluconeogenesis (Daim duab 3) yog qhov tseem ceeb ntawm kev thim rov qab ntawm glycolysis, thiab thawj substrates rau gluconeogenesis yog pyruvate, lactate, glycerol, thiab amino acids. Txhua yam ntawm cov substrates no tuaj yeem hloov mus rau qhov nruab nrab hauv txoj hauv kev gluconeogenic.
