Thaum lub sijhawm depolarization, sarcolemma feem ntau permeable rau: sodium ions.
Yuav ua li cas thaum lub sijhawm depolarization ntawm sarcolemma?
Kev khi Ach ua rau depolarization ntawm sarcolemma los ntawm qhib ion channel thiab tso Na + ions rau hauv cov leeg nqaijNa + ions diffuse rau hauv cov nqaij fiber ntau thiab depolarization tshwm sim. Raws li Ca + qib nce, Ca + ions khi nrog Troponin uas tshem tawm qhov thaiv ntawm Tropomyosin los ntawm Actin binding sites.
Depolarization ntawm sarcolemma txhais li cas?
Lub electrochemical gradient hla cov nqaij plasma daim nyias nyias (ntau sodium txav hauv tshaj li cov poov tshuaj tawm) ua rau lub zos depolarization ntawm lub tshuab kawg-phaj. Qhov no depolarization pib muaj peev xwm ua tauntawm cov leeg nqaij fiber ntau cell membrane (sarcolemma) uas hla hla cov nqaij fiber ntau.
Yuav ua li cas sarcolemma permeable rau?
tso tawm los ntawm synaptic vesicles thiab taug kev hla synaptic cleft thiab khi nrog cov protein receptors hauv sarcolemma. Qhov no ua rau cov sarcolemma ua rau permeable rau sodium ions uas ua rau lawv nkag mus; qhov no stimulates nqaij impulse.
Qhov twg ion channel hauv sarcolemma qhib thaum lub sijhawm depolarization?
Kev tsis sib haum xeeb ntawm sarcolemma ua rau qhib qhov hluav taws xob-gated Ca2+ channels thiab influx ntawm Ca2 + los ntawm qhov chaw extracellular. Qhov no Ca2+ pulse kuj tuaj yeem ua rau tso tawm ntawm intracellular Ca2+ los ntawm sarcoplasmic reticulum (Ca2+-induced Ca2 + tso tawm, CICR).
