Ib yam tshwj xeeb ntawm lub cev tiv thaiv kab mob uas muaj nyob hauv cov ntaub so ntswg, xws li daim tawv nqaij, thiab txhawb kev tiv thaiv kab mob los ntawm kev qhia cov tshuaj tiv thaiv ntawm nws qhov chaw rau lwm lub hlwb ntawm lub cev tiv thaiv kab mob. Lub dendritic cell yog ib hom phagocyte thiab ib hom antigen-presenting cell (APC).
Dendritic cells ua dab tsi hauv lub cev tiv thaiv kab mob?
Dendritic cells (DCs) sawv cev rau tsev neeg heterogeneous ntawm lub cev tiv thaiv kab mob uas txuas rau hauv lub cev thiab kev tiv thaiv kab mob. Lub luag haujlwm tseem ceeb ntawm cov hlwb innate no yog txhawm rau ntes, txheej txheem, thiab tam sim no antigens rau hloov lub cev tiv thaiv kab mob thiab kho lawv cov polarization rau hauv cov cell effector(1).
Dendritic hlwb muaj nuj nqi dab tsi?
Dendritic cells (DC) yog lub luag haujlwm rau pib ua txhua yam tshuaj tiv thaiv kab mob tiv thaiv kab mob Xws li, lawv yog tus tswv tswj hwm ntawm lub cev tiv thaiv kab mob thiab ua haujlwm no los ntawm kev sib txuas cov kab mob microbial sensing nta ntawm lub cev tiv thaiv kab mob hauv lub cev mus rau qhov tshwj xeeb ntawm cov lus teb hloov kho.
Lub luag haujlwm ntawm cov hlwb dendritic yog dab tsi hauv thawj lub cev tiv thaiv kab mob?
Dendritic hlwb yog nruab nrab rau qhov pib ntawm thawj lub cev tiv thaiv kab mob. Lawv tsuas yog cov tshuaj tiv thaiv kab mob tam sim no uas muaj peev xwm ua rau lub cev tsis muaj zog T hlwb, thiab yog li lawv yog qhov tseem ceeb hauv lub cim ntawm kev tiv thaiv kab mob.
Lub luag haujlwm ntawm lub cev dendritic ntawm daim tawv nqaij yog dab tsi?
Dendritic cells (DCs) yog cov tshuaj tiv thaiv tshwj xeeb uas nthuav tawm cov hlwb uas muaj ntau nyob rau hauv cov ntaub so ntswg xws li tawv nqaij uas lawv ua haujlwm raws li lub cev tiv thaiv kab mobCov tawv nqaij DCs tsiv mus rau cov qog ntshav qab zib uas lawv cuam tshuam nrog tsis zoo T hlwb los txhawb lub cev tiv thaiv kab mob rau cov kab mob, tshuaj tiv thaiv, qog thiab nws tus kheej-antigens.