“ Silent” kev hloov pauv: tsis hloov pauv cov amino acid, tab sis qee zaum tseem tuaj yeem muaj cov nyhuv phenotypic, xws li, los ntawm kev ua kom nrawm lossis ua kom qeeb ntawm cov protein synthesis, lossis los ntawm kev cuam tshuam splicing. Frameshift mutation: Tshem tawm lossis tso rau ntawm ntau lub hauv paus uas tsis yog ntau yam ntawm 3.
Kev hloov pauv yam twg yog kev hloov pauv ntsiag to?
Kev hloov pauv ntsiag to yog kev hloov pauv hauv DNA uas tsis muaj kev cuam tshuam rau lub cev phenotype. Lawv yog ib hom tshwj xeeb ntawm kev hloov pauv tsis tu ncuaCov kab lus ntsiag to hloov pauv feem ntau siv sib pauv nrog cov kab lus hloov pauv hloov pauv; Txawm li cas los xij, kev hloov pauv hloov pauv tsis yog ib txwm nyob twj ywm, lossis ua lwm yam.
Kev hloov pauv hloov pauv tuaj yeem tsis muaj tseeb?
Ib qho kev hloov pauv yog tsim los ntawm kev ntxig lossis deletionntawm ib lossis ntau lub hauv paus tshiab. Vim hais tias qhov kev nyeem ntawv pib ntawm qhov chaw pib, ib qho mRNA uas tsim los ntawm cov DNA hloov pauv yuav raug nyeem tawm ntawm tus ncej tom qab lub ntsiab lus ntawm qhov ntxig lossis tshem tawm, ua rau cov protein tsis muaj txiaj ntsig.
Puas yog ib qho kev hloov pauv hloov pauv tsis muaj tseeb uas ntsiag to lossis tshem tawm?
Kev hloov pauv ntsiag to tshwm sim thaum kev hloov pauv tsis hloov cov amino acid coded rau los ntawm codon ntawd. Ib qho kev hloov pauv hloov pauv yog ib qho kev ntxig lossis deletion uas hloov pauv cov ntawv nyeem ntawm tag nrho cov protein thiab tuaj yeem muaj kev cuam tshuam loj heev.
hom kev hloov pauv yog frameshift?
Kev hloov pauv hloov pauv yog kev hloov pauv caj ces tshwm sim los ntawm kev tshem tawm lossis tso rau hauv DNA ib ntusuas hloov txoj kev nyeem ib ntus.
