Proteasomes muaj nyob rau hauv lub cytoplasm thiab nyob rau hauv lub nuclei ntawm tag nrho cov eukaryotic hlwb, tab sis lawv cov txheeb ze abundance nyob rau hauv cov compartments yog heev variable. Hauv cytoplasm, proteasomes koom nrog centrosomes, cytoskeletal tes hauj lwm thiab sab nrauv ntawm endoplasmic reticulum (ER).
proteasome nyob qhov twg?
Proteasomes pom hauv txhua eukaryotes thiab archaea, thiab hauv qee cov kab mob. Hauv eukaryotes, proteasomes nyob rau hauv lub nucleus thiab hauv cytoplasm.
proteasomes ua haujlwm nyob qhov twg?
Cov proteasome yog multisubunit enzyme complex uas ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm cov protein uas tswj hwm lub voj voog ntawm tes thiab apoptosis, thiab yog li ntawd tau dhau los ua lub hom phiaj tseem ceeb rau kev tiv thaiv kab mob. kev kho mob.
YPuas yog proteasomes organelles?
Cov qauv siv lead ua ntawm cov proteasome qhia tias degradation ntawm ubiquitin-protein conjugates yog ua tiav los ntawm kev nthuav tawm cov protein substrate thiab translocating nws los ntawm cov channel mus rau hauv lub chamber uas muaj peptidase.
Qhov txawv ntawm lysosomes thiab proteasomes yog dab tsi?
Feem ntau, cov proteasome tuaj yeem degrade ib leeg cellular proteinsnyob rau hauv lub hom phiaj heev ntawm ubiquitin-proteasome system (UPS) thaum lysosomes degrade cytoplasmic Cheebtsam, suav nrog qee cov proteins, proteins. aggregates, thiab puas los yog cov organelles tshaj, los ntawm autophagy.
