Thaum cov kab mob primases (DnaG-hom) yog tsim los ntawm ib chav tsev protein (ib monomer)thiab ua ke RNA primers, AEP primases feem ntau yog tsim los ntawm ob chav sib txawv primase (ib heterodimer) thiab ua ke ob feem primers nrog ob RNA thiab DNA Cheebtsam.
Dab tsi yog primase enzyme tsim los ntawm?
Primases yog DNA-dependent RNA polymerases uas ua ke cov oligoribonucleotide primers tseem ceeb rau DNA replication. Hauv cov kab mob archaeal thiab eukaryotic, lub hauv paus tseem ceeb yog ib qho heterodimeric enzyme tsim los ntawm ib qho me me thiab loj subunit.
Yuav ua li cas hom enzyme yog primase?
Primase yog ib qho enzyme uas ua rau luv luv RNA sequences hu ua primers. Cov primers no ua qhov pib rau DNA synthesis. Txij li thaum primase tsim RNA molecules, cov enzyme yog ib hom RNA polymerase.
Qhia primase yog dab tsi?
Piav kev ua haujlwm ntawm enzyme primase thaum lub sijhawm dna replication. Lub enzyme hu ua RNA primase ua rau luv luv ntawm RNA primer uas yog ntxiv rau cov qauv DNA strand. … Qhov no RNA primer yog tsim nyog rau DNA polymerase (enzyme) kom pib ntxiv DNA nucleotides los ua ntu luv ntawm cov hlua khi.
Nucleotides dab tsi siv primase thiab nws ua dab tsi?
In eukaryotes, primase synthesizes ib luv RNA primer (8 - 12 nucleotides ntev) uas DNA polymerase α (pol α) elongates los ntawm lwm yam txog 20 nucleotides los tsim cov DNA primer (3). Pol α dissociates thiab pol δ lossis pol ε ua tiav qhov feem ntau ntawm DNA replication ntawm cov coj thiab lagging strands (4, 5).