Abstract. Pyrimidine synthesis tshwm sim hauv cytoplasm. Pyrimidine yog synthesized li lub nplhaib pub dawb thiab tom qab ntawd ib qho ribose-5-phosphate ntxiv rau cov txiaj ntsig ncaj qha nucleotides, whereas, hauv purine synthesis, lub nplhaib yog tsim los ntawm kev txuas atoms ntawm ribose-5-phosphate.
Pyrimidine tuaj yeem pom qhov twg?
Pyrimidine yog ib ntawm ob chav kawm ntawm heterocyclic nitrogenous bases pom nyob rau hauv cov nucleic acids DNA thiab RNA: hauv DNA cov pyrimidines yog cytosine thiab thymine, hauv RNA uracil hloov thymine.
pyrimidine catabolism tshwm sim nyob qhov twg?
Nucleotide Metabolism
Pyrimidine catabolism tshwm sim feem ntau hauv siab. Nyob rau hauv sib piv rau purine catabolism, pyrimidine catabolism yields heev soluble kawg khoom. Pyrimidine nucleotides hloov mus rau nucleosides los ntawm 5'-nucleotidase.
Dab tsi yog ob qho piv txwv ntawm pyrimidine?
Ib qho ntawm ob cov tshuaj sib txuas uas cov hlwb siv los ua lub tsev thaiv ntawm DNA thiab RNA. Piv txwv ntawm pyrimidines yog cytosine, thymine, thiab uracil. Cytosine thiab thymine yog siv los ua DNA thiab cytosine thiab uracil yog siv los ua RNA.
Yuav ua li cas kauj ruam ntawm pyrimidine biosynthesis tshwm sim hauv mitochondria?
De novo biosynthesis ntawm pyrimidine
Nplhaib tsim thiab Lub cev qhuav dej. Dihydroorotate ces nkag mus raumitochondria qhov twg nws yog oxidized los ntawm kev tshem tawm ntawm hydrogens. Qhov no tsuas yog mitochondrial kauj ruam hauv nucleotide rings biosynthesis. PRPP pub dawb rau pawg Ribose.
