Glucokinase yog ib qho enzyme uas pab txhawb phosphorylation ntawm qabzib mus rau qabzib-6-phosphate. Glucokinase tshwm sim hauv cov hlwb hauv daim siab thiab txiav txiav ntawm tib neeg thiab feem ntau lwm cov vertebrates.
txhais li cas los ntawm glucokinase?
: ib hexokinase pom tshwj xeeb hauv lub siab uas ua rau cov phosphorylation ntawm qabzib.
YGluckinase gene yog dab tsi?
GCK noob muab cov lus qhia ua cov protein hu ua glucokinase. Cov protein no ua lub luag haujlwm tseem ceeb hauv kev rhuav tshem cov suab thaj (tshwj xeeb yog cov piam thaj) hauv lub cev. Glucokinase feem ntau pom muaj nyob rau hauv daim siab thiab hauv beta hlwb hauv pancreas.
Thaum twg siv glucokinase?
Glucokinase ua haujlwm raws li cov piam thaj hauv cov beta cell los ntawm tswj tus nqi ntawm cov piam thaj nkag mus rau hauv glycolytic txoj hauv kev (glucose phosphorylation) thiab nws cov metabolism tom qab. Hauv daim siab, glucokinase ua lub luag haujlwm tseem ceeb hauv lub peev xwm khaws cov piam thaj li glycogen, tshwj xeeb tshaj yog nyob rau hauv lub xeev postprandial.
YPuas yog glucokinase ib hexokinase?
Glucokinase (GK) belongs to cov tsev neeg hexokinase (Grossbard thiab Schimke, 1966). Nws catalyzes phosphorylation ntawm cov piam thaj molecule los tsim cov piam thaj 6-phosphate thiab ua lub luag haujlwm tseem ceeb hauv kev siv cov piam thaj thiab cov metabolism hauv lub siab thiab txiav (Al-Hasani li al., 2003).
