Aromatization feem ntau tshwm sim thaum qhov hloov pauv loj ntawm testosterone ntau lawm tshwm sim, xws li thaum txhaj tshuaj anabolic steroids. Qhov loj ntawm testosterone yuav raug pom tias yog ib qho dhau los ntawm tib neeg lub cev thiab aromatization yuav tshwm sim hauv kev sim kom sib npaug ntawm cov testosterone tshiab nrog ntau dua cov tshuaj estrogen.
Dab tsi ua rau tsim cov tshuaj estrogen?
Thaum kawg ntawm folliculogenesis, thecal hlwb luteinize los tsim lub corpus luteum tom qab ovulation. (b) Cell-specific estrogen synthesis nyob rau hauv zes qe menyuam. Kev tsim cov tshuaj estrogens pib nrog cov synthesis ntawm pregnenolone los ntawm cov roj cholesterol, catalyzed los ntawm cytochrome P450 sab saw cleavage enzyme(P450scc).
Dab tsi ua rau testosterone aromatization?
Aromatization tshwm sim thaum aromatase complex converts C19 androgen substrates rau C18 estrogenshauv peb qhov kev sib txuas: (1) hydroxylation (2) oxidation thiab (3) demethylation.
Dab tsi ua rau muaj zog aromatase?
Kev hloov pauv ntawm cov khoom siv caj ces cuam tshuam nrog CYP19A1 gene ua rau aromatase ntau dua syndrome. CYP19A1 noob muab cov lus qhia ua ib qho enzyme hu ua aromatase. Cov enzyme no hloov cov chav kawm ntawm cov tshuaj hormones hu ua androgens, uas koom nrog hauv kev loj hlob ntawm txiv neej, rau ntau hom tshuaj estrogen.
aromatization ntawm cov tshuaj hormones yog dab tsi?
Abstract. Lub Hom Phiaj: Aromatization yog cov txheej txheem biochemical uas aromatase catalyzes hloov pauv ntawm testosterone rau hauv estradiol, txoj hauv kev rau kev sib txuas ntawm estrogens. Thaum txhim kho, nws tuaj yeem ua rau hyperestrogenism, qhov kev pheej hmoo paub txog kev mob qog noj ntshav gynecological.
