Th2-hom cytokines suav nrog interleukins 4, 5, thiab 13, uas cuam tshuam nrog kev nce qib ntawm IgE thiab eosinophilic cov lus teb hauv atopy, thiab kuj interleukin-10, uas muaj ntau cov lus teb anti-inflammatory. Tshaj dhau, Th2 cov lus teb yuav tawm tsam Th1 mediated microbicidal action.
Th2 tiv thaiv kab mob dab tsi?
Th2 hlwb koom nrog hauv hom 2 lub cev tiv thaiv kab mob, uas yog tseem ceeb rau kev tshem tawm cov kab mob ntxiv thiab kab mob kab mob. Lawv tsim IL-4, IL-5, IL-10, thiab IL-13, uas yog ib qho tseem ceeb rau induction thiab kev loj hlob ntawm humoral tiv thaiv kab mob.
Puas Th2 teb tiv thaiv kab mob?
Hauv cov ntsiab lus, peb cov ntaub ntawv qhia tias ua kom Th2 cov lus teb inhibits inflammatory mob caj dabMechanistically, IL-4 / IL-13-STAT6 kev taw qhia txoj hauv kev induces macrophage polarization rau hauv cov tshuaj tiv thaiv macrophages rau hauv cov pob qij txha. Tsis tas li ntawd, eosinophils tau qhib thiab pab ntxiv rau kev daws teeb meem ntawm tus kab mob.
Th2 cell yog dab tsi?
Th2 hlwb yog dab tsi? … Th2 hlwb mediate qhov ua kom thiab kev saib xyuas ntawm humoral, lossis antibody-mediated, kev tiv thaiv kab mob tiv thaiv kab mob hauv hlwb, kab mob, allergens, thiab toxinsTh2 hlwb kho cov haujlwm no los ntawm kev tsim ntau yam cytokines xws li IL-4, IL-5, IL-6, IL-9, IL-13, thiab IL-17E (IL-25).
Qhov txawv ntawm Th1 thiab Th2 yog dab tsi?
Th1 hlwb txhawb lub cev tiv thaiv kab mob, koom nrog inhibition ntawm macrophage activation thiab txhawb B hlwb los tsim IgM, IgG1. Th2 txhawb kev tiv thaiv kab mob humoral, txhawb nqa B cell proliferation thiab induces antibody ntau lawm (IL-4).
