Vim li cas thalidomide thiaj li muag raws li kev sib tw racemic?

2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38

Muaj ib chiral carbon nyob rau hauv thalidomide molecule. Cov tshuaj tau tsim thiab ua lag luam raws li kev sib xyaw ntawm cov haiv neeg ntawm (+)(R)-thalidomide thiab (-)(S)-thalidomide. … Vim protein molecules yog chiral, lawv muaj qhov sib txawv nrog ob enantiomers ntawm cov tshuaj chiral

Thalidomide cuam tshuam li cas rau chirality?

Thalidomide yog chiral moleculethiab cov tshuaj uas tau muag yog 50/50 sib xyaw ntawm sab laug thiab sab xis molecules. Thaum sab laug molecule ua tau zoo, sab tes xis yog tshuaj lom heev.

Thalidomide sib cais li cas?

Cov thalidomide enantiomers, muab rho tawm los ntawm cov qauv nrog diethyl ether, tau zoo sib cais ntawm chiral HPLC kem ntawm vancomycin nyob ruaj khov theem thiab theem mobile ntawm 14% acetonitrile hauv 20 mM ammonium formate hloov kho rau pH 5.4; Lawv cov concentrations tau txiav txim siab nrog phenacetin raws li tus qauv sab hauv ntawm 220 nm …

Puas yog thalidomide muag raws li ib qho isomer?

Thalidomide tsuas muaj ib qho chiral atom thiab thiaj li muaj xws li ob enantiomers.

tshuaj pleev thalidomide yog dab tsi?

Kev piav qhia. (S)-thalidomide yog a 2-(2, 6-dioxopiperidin-3-yl)-1H-isoindole-1, 3(2H)-dione uas muajS-configuration ntawm lub chiral chaw. Nws muaj lub luag haujlwm ua tus neeg sawv cev teratogenic. Nws yog ib qho enantiomer ntawm ib (R)-thalidomide.