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Nyob rau hauv reductive amination ammonia reacts nrog?

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Nyob rau hauv reductive amination ammonia reacts nrog?
Nyob rau hauv reductive amination ammonia reacts nrog?

Video: Nyob rau hauv reductive amination ammonia reacts nrog?

Video: Nyob rau hauv reductive amination ammonia reacts nrog?
Video: neeg yug nyob rau nas xyoo 2024, Tej zaum
Anonim

Kev txo qis ntawm aldehydes lossis ketones yog ib txoj hauv kev zoo tshaj plaws ntawm kev tsim cov amines, tshwj xeeb tshaj yog nyob rau hauv kev lag luam. Txhawm rau tsim cov amino acids ntawm lub ntsuas ntsuas, cov khoom pib yog α-keto acid. Ammonia reacts nrog the α-keto acid muab imine.

Yuav txo qis amination hauv biology yog dab tsi?

Reductive amination, lossis kev hloov pauv ntawm pawg carbonyl mus rau ib qho amine los ntawm iminium ion nruab nrab (Tshooj 1), yog ib qho tseem ceeb tshaj plaws rau kev sib txuas ntawm chiral amines, ib pab pawg ua haujlwm uas muaj feem ntau ntawm cov khoom me me ntawm cov khoom siv roj ntsha.

Kev txo qis amination siv rau dab tsi?

Kev txo qis ntawm aldehydes lossis ketones yog txoj hauv kev zoo tshaj plaws ntawm kev tsim cov amines, tshwj xeeb tshaj yog ntawm kev lag luam. Txhawm rau tsim cov amino acids ntawm lub ntsuas ntsuas, cov khoom pib yog α-keto acid. Ammonia reacts nrog α-keto acid muab ib qho imine.

Lub ntsiab lus ntawm kev txiav txim yog dab tsi?

Amination yog txheej txheem uas ib pawg amine tau nkag mus rau hauv cov organic molecule. Hom tshuaj tiv thaiv no yog qhov tseem ceeb vim tias cov tshuaj organonitrogen muaj ntau zuj zus.

Dab tsi yog cov amines tseem ceeb?

Primary (1°) amines-Primary amines arise when one of three hydrogen atoms in ammonia is replaced by alkyl or aromatic group Tseem ceeb thawj alkyl amines suav nrog, methylamine, feem ntau amino acids, thiab tus neeg sawv cev buffering tris, thaum thawj aromatic amines muaj xws li aniline.

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