Levetiracetam yog tshem tawm ntawm lub cev ncig los ntawm lub raum tso tawmraws li cov tshuaj tsis hloov pauv uas sawv cev rau 66% ntawm cov tshuaj noj. Tag nrho lub cev tshem tawm yog 0.96 mL / min / kg thiab lub raum tshem tawm yog 0.6 mL / min / kg.
Cov tshuaj twg raug tshem tawm thaum lub sij hawm lim ntshav?
Cov Tshuaj Dialyzable
- B - Barbiturates.
- L - Lithium.
- I - Isoniazid.
- S - Salicylates.
- T - Theophyline / Caffeine (ob leeg yog methylxanthines)
- M - Methanol, metformin.
- YE - Ethylene glycol.
- D - Depakote, dabigatran.
Keppra metabolized li cas?
kwv yees li 34% ntawm koob tshuaj levetiracetam yog metabolised thiab 66% yog tawm hauv cov zis unmetabolised; Txawm li cas los xij, cov metabolism tsis yog mob siab tab sis tshwm sim hauv cov ntshav los ntawm hydrolysis.
Puas yog qaug dab peg nrog kev lim ntshav?
Kev qaug dab peg tsis tshua muaj tshwm sim ntawm cov neeg mob hemodialysis [1]. Muaj ntau qhov ua rau qaug dab peg ntawm cov neeg mob hemodialysis. Feem ntau, kev qaug dab peg tshwm sim thaum lub sij hawm lossis sai tom qab cov txheej txheem hemodialysis vim yog cov kev hloov pauv ntawm hemodynamic thiab biochemical cuam tshuam nrog cov txheej txheem [1].
Puas levetiracetam puas yuav tsum tau kho lub raum?
Txawm hais tias nws ua tau zoo, qhov ntau npaum li cas rau cov neeg mob raum tsis zoo yuav tsum raug txo. Txij li thaum levetiracetam tshem tawm ntawm lub raum yog 66% hauv cov neeg mob lub raum tsis zoo, nws ib nrab lub neej yuav kav ntev li 25 teev.
