Kev hloov pauv ntsiag to yog kev hloov pauv hauv DNA uas tsis muaj kev cuam tshuam rau lub cev phenotype. Lawv yog ib hom kev hloov pauv nruab nrab. Cov kab lus ntsiag to mutation feem ntau siv sib hloov nrog cov kab lus hloov pauv; Txawm li cas los xij, kev hloov pauv hloov pauv tsis yog ib txwm nyob twj ywm, lossis ua lwm yam.
Ib qho piv txwv ntawm kev hloov pauv ntsiag to yog dab tsi?
Silent mutations yog cov hloov pauv uas ua rau tsis muaj kev hloov pauv ntawm cov amino acid lossis amino acid functionality thaum tus xa xov hloov pauv RNA (mRNA) raug txhais. Piv txwv li, yog tias codon AAA hloov pauv los ua AAG, tib cov amino acid - lysine - yuav raug muab tso rau hauv cov saw peptide.
Lub ntsiab lus ntawm kev hloov pauv ntsiag to yog dab tsi?
Kev hloov pauv ntsiag to yog hom kev hloov pauv uas tsis ua rau muaj kev hloov pauv tseem ceeb hauv cov amino acid. Yog li ntawd, cov protein tseem ua haujlwm. Vim li no, cov kev hloov pauv tau suav tias yog lawv qhov kev hloov pauv nruab nrab.
Vim li cas thiaj muaj kev sib hloov ntsiag to?
Kev hloov ntsiag to tshwm sim thaum kev hloov pauv ntawm DNA ntu hauv ib feem ntawm cov protein-coding ntawm cov noob tsis cuam tshuam rau qib ntawm cov amino acids uas tsim cov proteinQhov kev hloov no feem ntau tshwm sim ntawm qhov thib peb txoj haujlwm ntawm codon tseem hu ua txoj haujlwm wobble.
Kev hloov ntsiag to cuam tshuam li cas rau cov protein?
"Tseeb" kev hloov pauv: tsis hloov cov amino acid, tab sis qee zaum tseem tuaj yeem muaj cov nyhuv phenotypic, piv txwv li, los ntawm kev ua kom nrawm lossis qeeb ntawm cov protein synthesis, lossis los ntawm kev cuam tshuam splicing.
