Ntawm mRNAs, poly(A) tus Tsov tus tw tiv thaiv mRNA molecule los ntawm enzymatic degradation nyob rau hauv cytoplasm thiab pab nyob rau hauv transcription termination, export ntawm mRNA los ntawm lub nucleus, thiab kev txhais lus. Yuav luag tag nrho eukaryotic mRNAs yog polyadenylated, tshwj tsis yog tsiaj replication-dependent histone mRNAs.
Puas tsuas yog prokaryotic mRNAs yog polyadenylated ntawm 3 kawg?
Lub 3 '-kawg ntawm ob qho tib si prokaryotic thiab eukaryotic mRNA yog polyadenylated, tab sis cov poly(A) tracts ntawm prokaryotic mRNA feem ntau luv, xws li ntawm 15 mus rau 60 adenylate residues. thiab koom nrog tsuas yog 2-60% ntawm cov molecules ntawm ib hom mRNA.
Qhov twg mRNA tsis yog polyadenylated?
The mRNAs uas encode feem ntau ntawm cov proteins histone hauv metazoans, replication-dependent histone mRNAs, tsuas yog paub eukaryotic cellular mRNAs uas tsis yog polyadenylated, thiab ntxiv rau., introns yeej tsis pom nyob rau hauv cov histone mRNAs.
Puas splicing tshwm sim ua ntej polyadenylation?
Rau cov ntawv sau luv luv, RNA splicing feem ntau ua raws li kev sib cais thiab polyadenylation ntawm 3′ kawg ntawm thawj cov ntawv sau tseg. Tab sis rau ntev transcription units uas muaj ntau exons, splicing ntawm exons nyob rau hauv nascent RNA feem ntau pib ua ntej transcription ntawm cov noob tiav
Muaj mRNA sib txawv tuaj yeem tsim los ntawm tib lub noob?
Txawm li cas los xij, kev sib txuas tso cai rau cov txheej txheem hu ua lwm txoj kev sib txuas, uas ntau tshaj ib mRNA tuaj yeem tsim los ntawm tib lub noob. … Qhov no ua rau peb mRNA mRNAs paub tab, txhua tus uas txhais ua cov protein nrog cov qauv sib txawv.
