Thaum elongation, tRNAs txav los ntawm qhov chaw A, P, thiab E ntawm ribosome, raws li qhia saum toj no. Cov txheej txheem no rov ua dua ntau zaus thaum cov codons tshiab tau nyeem thiab cov amino acids tshiab ntxiv rau cov saw.
ribosome ua dab tsi thaum lub sij hawm elongation?
Thaum lub sijhawm elongation, lub ribosome txuas ntxiv txhais txhua codon nyob rau hauv lem. Txhua tus sib raug zoo amino acid yog ntxiv rau cov saw loj hlob thiab txuas ntawm daim ntawv cog lus hu ua peptide daim ntawv cog lus. Elongation txuas ntxiv mus txog thaum tag nrho cov codons tau nyeem.
Qhov chaw twg hauv ribosome nqa cov protein elongation?
Cov hauv paus ntawm elongation yog tib yam hauv prokaryotes thiab eukaryotes. Lub ribosome tsis zoo muaj peb qhov chaw: A site binds incoming aminoacyl tRNAs; the P site khi tRNAs nqa cov saw hlau loj hlob tuaj; E qhov chaw tso tawm tRNAs dissociated kom lawv tuaj yeem rov them nrog cov amino acids.
P site ntawm ribosome ua dab tsi?
Ribosome Structure
P site, hu ua peptidyl site, khi rau tRNA tuav cov saw polypeptide loj hlob ntawm cov amino acids. Qhov chaw A (chaw txais khoom), khi rau aminoacyl tRNA, uas tuav cov amino acid tshiab ntxiv rau cov saw hlau polypeptide.
Qhov chaw ntawm ribosome yog qhov twg nyeem codon?
Tus qauv qub ob lub xeev tau tshaj tawm tias ribosome muaj ob qhov chaw sib khi rau tRNA, P-site thiab A-site. A-site khi rau cov khoom aminoacyl-tRNA uas muaj cov tshuaj tiv thaiv codon rau cov codon sib xws hauv mRNA nthuav tawm hauv A-site.
