Thaum cov nqaij ntshiv, calcium ions raug tso tawm ntawm nws lub khw hauv sarcoplasmic reticulum, mus rau hauv sarcoplasm (cov leeg). … Calcium yog pumped rov qab mus rau hauv SR kom txo cov calcium ion concentration nyob rau hauv lub sarcoplasm, so cov leeg (tua tawm contraction).
Dab tsi ua rau calcium tso tawm los ntawm sarcoplasmic reticulum?
Thaum lub sijhawm txhawb nqa ntawm cov leeg nqaij, lub cev muaj zog neuron tso tawm cov neurotransmitter acetylcholine, uas tom qab ntawd khi rau tom qab synaptic nicotinic acetylcholine receptor. … Lub sab hauv ntws ntawm calcium los ntawm L-hom calcium channels activates ryanodine receptors tso calcium ions los ntawm sarcoplasmic reticulum.
Lub hom phiaj ntawm calcium uas tsim cov calcium tso tawm yog dab tsi?
Calcium-induced calcium tso tawm yog ib qho cov txheej txheem dav dav uas cov hlwb feem ntau siv los ua kom muaj zog Ca++ signals hauv plawv hlwb, cov txheej txheem no yog ua haujlwm ntawm voltage-gated L-type Ca++ channels (Cav 1), nyob rau hauv cov ntshav plasma, thiab ryanodine receptor channels, nyob rau hauv lub sarcoplasmic reticulum.
Ca2+ tso tawm los ntawm sarcoplasmic reticulum li cas?
Calcium ion tso tawm los ntawm SR, tshwm sim nyob rau hauv junctional SR/terminal cisternae los ntawm ryanodine receptor (RyR) thiab paub tias yog calcium spark. Muaj peb hom ryanodine receptor, RyR1 (hauv cov leeg pob txha), RyR2 (hauv cov leeg plawv) thiab RyR3 (hauv lub hlwb).
Ca2+ tso tawm ntawm SR ua dab tsi?
Excitation–contraction (E–C) coupling piav qhia txog cov txheej txheem txuas depolarisation ntawm daim nyias nyias thiab tso tawm Ca2+ los ntawm SR, uas muab lub teeb liab rau cov leeg nqaij.
