Plaques, cov kab mob txawv txav ntawm cov khoom tawg, tsim ntawm cov paj hlwb. Cov paj hlwb tuag thiab tuag muaj cov tangles, uas yog tsim los ntawm cov kab sib tw ntawm lwm cov protein.
Pob plaques ua tangles?
Cov Plaques thiab Tangles ua rau Dementia li cas? Qhov muaj cov plaques nyob ib ncig ntawm cov neuron ua rau lawv tuag, tejzaum nws ua rau lub cev tiv thaiv kab mob hauv thaj chaw tam sim ntawd. Tangles tsim sab hauv ntawm cov neurons thiab cuam tshuam nrog cov tshuab cellular siv los tsim thiab rov ua dua cov protein, uas thaum kawg tua cov cell.
Dab tsi yog plaques thiab tangles nyob rau hauv ib txwm muaj hnub nyoog?
Cov plaques yog cov kab mob txawv txav ntawm cov proteinhu ua beta amyloid. Cov tangles yog bundles ntawm twisted filaments ua los ntawm ib tug protein hu ua tau. Plaques thiab tangles nres kev sib txuas lus ntawm paj hlwb thiab ua rau lawv tuag. Vascular dementia yog kev paub tsis meej los ntawm kev puas tsuaj rau cov hlab ntsha hauv lub hlwb.
plaques thiab tangles tsim hauv lub hlwb li cas?
Nws yog tsim los ntawm kev tawg ntawm cov protein ntau dua, hu ua amyloid precursor protein. Ib daim ntawv, beta-amyloid 42, tau xav tias yog tshuaj lom tshwj xeeb. Hauv Alzheimer's lub hlwb, qhov txawv txav ntawm qhov tshwm sim ib txwm muaj protein ntau ua ke los tsim cov plaques uas sib sau ntawm cov neurons thiab cuam tshuam kev ua haujlwm ntawm tes.
Puas yog cov plaques thiab tangles li qub?
Ob leeg amyloid plaques thiab neurofibrillary tangles yog tsim ntawm cov protein uas tseem tshwm sim ua ib feem ntawm cov txheej txheem kev laus ib txwm, tab sis hauv cov neeg uas muaj Alzheimer's-hom dementias, cov proteins no. uas tsim tsa muaj ntau dua.
