Txoj hauv kev zoo tshaj plaws rau thioester suav nrog cov tshuaj tiv thaiv ntawm cov kua qaub chloride nrog alkali hlau ntsev ntawm thiol: RSNa + R′COCl → R′COSR + NaCl. Lwm txoj hauv kev ua rau kev hloov pauv ntawm halides los ntawm alkali hlau ntsev ntawm thiocarboxylic acid.
Acyl phosphate tsim li cas?
Txoj kev siv ntau tshaj plaws ntawm kev sib xyaw acyl phosphates hauv qhov chaw kuaj mob yog los ntawm reacting yam hu ua acyl chloride nrog phosphatesCov tshuaj tiv thaiv no ua rau tsim cov pa roj carbon-oxygen daim ntawv cog lus xav tau. rau acyl phosphate thiab carbon-chlorine daim ntawv cog lus yog tawg los ntawm acyl chloride.
Tioester hydrolysis yog dab tsi?
Hydrolysis ntawm thioesters
Cov acyl pawg ntawm thioester tuaj yeem hloov mus rau cov dej molecule hauv cov tshuaj tiv thaiv hydrolysis, uas ua rau carboxylate. Ib qho piv txwv ntawm thioester hydrolysis yog hloov pauv ntawm (S)-citryl CoA rau citrate hauv lub voj voog citric acid (tseem hu ua Krebs cycle).
Vim li cas thioester yog qhov kev xaiv zoo dua rau kev hloov pauv acyl dua li ester li niaj zaus?
Tsis tas li ntawd, C-S daim ntawv cog lus tsis muaj zog dua li C-O daim ntawv cog lus, thiab thiolate (los yog thiol, yog tias protonated ) yog ib pawg tawm zoo dua li alkoxide (lossis cawv). Cov xwm txheej no txhua tus ua rau thioester feem ntau ua tus neeg sawv cev zoo dua li ester.
Puas yog daim ntawv cog lus thioester yog daim ntawv cog lus?
Thioester daim ntawv cog lus yog, txawm li cas los xij, cov txheej txheem tseem ceeb thiab kev ua haujlwm ntawm qee cov proteins, suav nrog C3. … Nws yog daim ntawv cog lus no uas tau lees paub los ntawm C3 lub peev xwm los tsim covalent daim ntawv cog lus nrog cell-nto macromolecules, lub cev tiv thaiv kab mob, thiab ntau yam me me molecules hauv kev daws (LAW thiab LEVINE 1977; LAW etal.
