Ornithine yog ib qho ntawm nruab nrab metabolites ntawm lub voj voog urea uas tsis suav nrog hauv cov proteins ntuj. Es tsis txhob, nws yog tsim nyob rau hauv lub cytosol los ntawm arginine thiab yuav tsum tau thauj mus rau hauv lub mitochondria, qhov twg nws yog siv los ua ib tug substrate rau lub enzyme OTC los ua citrulline.
Vim li cas tej zaum ornithine ib txwm tshwm sim amino acid tsis raug muab tso rau hauv cov protein?
Qee cov amino acids ntuj, xws li norleucine, yog misincorporated translationally rau hauv cov proteins vim tsis ncaj ncees lawm ntawm cov protein-synthesis txheej txheem. Ntau cov amino acids, xws li ornithine, yog metabolic intermediates tsim biosynthetically, tab sis tsis suav nrog kev txhais lus rau hauv cov protein.
YPuas yog ornithine siv rau hauv cov protein synthesis?
14.4.
Ornithine thiab arginine koom nrog hauv ob qho tib si ureavoj voog thiab creatine biosynthesis. Arginine tsis yog tsuas yog pab pawg neeg guanidino pub rau creatine synthesis, tab sis kuj yog lub substrate rau protein tsev thiab nitric oxide tsim.
Yuav ua li cas cov amino acid tsis pom nyob rau hauv cov protein?
Ib qho amino acid tsis pom hauv cov protein yog β-Alanine.
YPuas yog ornithine yog ib qho tseem ceeb amino acid?
Ornithine yog ib yam tsis tseem ceeb amino acid ua los ua ib qho nruab nrab molecule hauv urea voj voog. Nws yog ib qho tseem ceeb substrate rau synthesis ntawm proline, polyamines thiab citrulline.
