Cov txheej txheem:
- Vim li cas NHEJ suav hais tias yog qhov ua yuam kev yuam kev?
- Puas yog homologous recombination yuam kev prone?
- NHEJ kho dab tsi?
- Yuav ua li cas kho qhov yuam kev yog dab tsi?
Video: Vim li cas nhej error prone?
2024 Tus sau: Fiona Howard | [email protected]. Kawg hloov kho: 2024-01-10 06:38
Nws yog dav xav tias C-NHEJ kuj yog qhov ua yuam kev, vim cov txheej txheem kho kho cuam tshuam nrog kev ua tiav ntawm DNA xaus ntawm qhov chaw tawg, uas tuaj yeem ua rau tshem tawm nucleotideYog li, kev koom nrog cov DNA no xaus ntawm C-NHEJ hauv thaj av uas tau sau tseg tuaj yeem yog mutagenic thiab/lossis tuag rau cov hlwb.
Vim li cas NHEJ suav hais tias yog qhov ua yuam kev yuam kev?
Ib qho tseem ceeb, NHEJ yog txoj hauv kev kho qhov yuam kev. Vim cov txheej txheem tsis siv tus qauv ua ke, kev sib xyaw ntawm cov DNA duplexes uas tsis muaj tseeb yuav ua rau muaj kev tshem tawm lossis tso cov khub hauv paus.
Puas yog homologous recombination yuam kev prone?
Homologous recombination (HR) yog cov txheej txheem evolutionarily kev txuag uas ua lub luag haujlwm tseem ceeb hauv kev sib npaug ntawm cov caj ces ruaj khov thiab ntau haiv neeg. HR feem ntau suav hais tias tsis muaj qhov yuam kev, tab sis ntau qhov kev tshawb fawb tau pom tias HR tuaj yeem ua yuam kev.
NHEJ kho dab tsi?
Non-homologous end joining (NHEJ) is a pathway that repairs two-strand breaks in DNA… Thaum lub overhangs tau zoo kawg nkaus, NHEJ feem ntau kho qhov tawg kom raug. Kev kho tsis ncaj ncees ua rau poob ntawm nucleotides kuj tuaj yeem tshwm sim, tab sis muaj ntau dua thaum cov overhangs tsis sib xws.
Yuav ua li cas kho qhov yuam kev yog dab tsi?
RecA protein, txhawb nqa los ntawm ib leeg-stranded DNA, koom nrog hauv kev tsis ua haujlwm ntawm kev tawm tsam (LexA) ntawm SOS cov noob caj noob ces thiaj li ua rau cov lus teb. Nws yog qhov kev kho tsis raug uas ua rau muaj txiaj ntsig zoo rau DNA hloov pauv tau pom nyob rau hauv ntau hom.
Pom zoo:
Kev hloov pauv feem ntau tsis zoo vim li cas lossis vim li cas ho tsis?
Feem ntau ntawm kev hloov pauv yog nruab nrab ntawm lawv cov teebmeem ntawm cov kab mob uas lawv tshwm sim. Kev hloov pauv tau zoo tuaj yeem ua ntau dua los ntawm kev xaiv ntuj. Kev hloov pauv tsis zoo yuav ua rau muaj kab mob caj ces lossis mob qog noj ntshav .
Vim li cas thiab vim li cas thiaj txhais tau?
Txhua qhov laj thawj thiab qhov laj thawj, ib yam li hauv Nws tau mus rau qhov laj thawj thiab yog li ntawm lub koom haum kev saws me nyuam txoj cai thiab cov txheej txheem. Cov lus no niaj hnub no yog redundancy vim yog vim li cas thiab yog li ntawd txhais tau tib yamYav tas los, txawm li cas los xij, vim li cas thiaj qhia qhov laj thawj rau qee yam thiab yog li ntawd nws los ua li cas.
Puas tib neeg hloov zuj zus los ntawm chimps vim li cas los yog vim li cas ho tsis?
Nws yog ib lo lus teb yooj yim: Tib neeg tsis tau hloov zuj zus los ntawm chimpanzees los yog lwm yam zoo kawg nkaus apes uas nyob niaj hnub no. Peb sib koom ib tug poj koob yawm txwv uas nyob kwv yees li 10 lab xyoo dhau los . Puas tib neeg hloov zuj zus los ntawm apes?
Kev kho hauv zej zog puas txo qis vim li cas lossis vim li cas ho tsis?
Kev kho cov neeg koom nrog hauv chaw pw hav zoov tag nrho tsis muaj qhov sib txawv ntawm cov nqi rov ua dua los ntawm pab pawg ntawm cov neeg raug foob thiab raug kaw. Txawm hais tias tej zaum yuav muaj qee qhov kev tshawb fawb qhia qhov sib txawv me me-tshwj xeeb yog cov kev pab cuam nrog cov kev kho mob-cov txiaj ntsig tag nrho tsis txawv ntawm kev txo qis kev ua phem rau yav tom ntej .
Yuav sau li cas vim li cas thiab yog vim li cas?
Kev txhais ntawm yog vim li cas thiab (tus) yog li ntawd: yog vim li cas rau ib yam Nws piav qhia vim li cas thiab yog li ntawd ntawm tus nqi nce . Yuav ua li cas thiab yog vim li cas? Txhua qhov laj thawj thiab qhov laj thawj, ib yam li hauv Nws tau mus rau qhov laj thawj thiab yog li ntawm lub koom haum kev saws me nyuam txoj cai thiab cov txheej txheem.
