Nyob rau hauv tib neeg embryos, feem ntau aneuploidies ua rau tuag, ua rau nchuav menyuam, lossis tsis ua rau cev xeeb tub. Lub sijhawm ntawm aneuploidy nce nrog lub hnub nyoog ntawm tus poj niam; Thaum tus poj niam muaj hnub nyoog 40 xyoo, kwv yees li 80% ntawm nws embryos yog aneuploid.
Yuav txawv txav embryos kho lawv tus kheej li cas?
Kev kuaj caj ces siv los tshuaj ntsuam embryos rau aneuploidy ua ntej in vitro fertilization (IVF) yog txhais tau tias pab kom tsis txhob nchuav menyuam. Tab sis ib txoj kev tshawb fawb tshiab qhia tau hais tias ntau tus embryos aneuploid ua tau nws tus kheej hauv plab… Qhov ntawd hu ua aneuploidy, thiab nws yog qhov ua rau muaj li 60% ntawm kev nchuav menyuam.
% pes tsawg ntawm blastocysts yog aneuploid?
Txawm tias cov poj niam hnub nyoog qis dua 35 xyoo, tus nqi aneuploidy zoo li ntau dua 50% ntawm cov cleavage-stage embryos thiab nce mus txog 30-40%hauv blastocysts (Table 1 thiab 2). Nrog rau cov poj niam uas muaj hnub nyoog dhau los, nws yuav dhau los ua qhov hloov pauv tus menyuam mos uas tsis muaj peev xwm ua rau muaj sia nyob.
Puas aneuploid embryo kho lawv tus kheej?
Qhov kev tshawb pom tias embryos nthuav tawm cov kab mob chromosomal txawv txav yog qhov ua tau zoo dua li qhov kev xav yav dhau los tuaj yeem hloov peb txoj hauv kev rau IVF thiab nce kev ua tiav. … Tam sim no cov kws tshawb fawb hauv Asmeskas tau pom tias aneuploid embryos muaj peev xwm tsim kho tus kheejthiab muaj peev xwm loj hlob mus rau cov menyuam mos noj qab haus huv.
Yuav ua li cas feem pua ntawm cov embryos implanted ciaj sia?
Tus ciaj sia taus yog 69% rau thawed zygotes, 85% rau D3 embryos, thiab 88% rau blastocysts [Table 1]. Tus nqi cog rau ib tus lej thawed yog 10% rau zygotes, 12% rau D3 embryos, thiab 14% rau blastocysts.
