Definition: A receptor-mediated endocytosis txheej txheem uas ua rau muaj kev txav ntawm cov receptors los ntawm cov ntshav plasma mus rau sab hauv ntawm tes. Cov txheej txheem pib thaum cell nto receptors yog monoubiquitinated tom qab ligand-induced activation.
Dab tsi ua rau receptor internalization?
Internalization ntawm G-protein-coupled receptors (GPCRs) tshwm sim nyob rau hauv cov lus teb rau agonist ua kom cov receptors thiab ua rau rov faib cov receptors tawm ntawm cov ntshav plasma mus rau endosomes.
Dab tsi yog internalization hauv biology?
Biology. Hauv kev tshawb fawb xws li biology, internalization yog lwm lo lus rau endocytosis, nyob rau hauv cov molecules xws li cov proteins yog engulfed los ntawm cell membrane thiab kos rau hauv lub cell.
Tus receptors puas tuaj yeem nyob hauv?
Cell membrane receptors khi rau lawv cov ligands thiab tsim ib qho complex uas tuaj yeem ua rau sab hauv.
Dab tsi yog receptor internalization thiab rov ua dua?
Tus nqi ntawm internalization (txhais tau tias tus nqi ntawm qhov kev hloov pauv ntawm cov receptors saum npoo) yog tus nqi ntawm cov receptors tuaj txog ntawm cov plasma membrane los ntawm kev rov ua dua tus nqi ntawm cov receptors tawm plasma membrane los ntawm endocytosis.