Hauv kev txhim kho tshuaj, kev txhim kho preclinical, tseem hu ua kev tshawb fawb txog kev kho mob lossis kev tshawb fawb tsis pom zoo, yog ib theem ntawm kev tshawb fawb uas pib ua ntej kev sim tshuaj thiab thaum lub sij hawm qhov tseem ceeb ua tau, kev tshuaj ntsuam xyuas dua thiab cov ntaub ntawv kev nyab xeeb tshuaj raug sau, feem ntau hauv cov tsiaj sim.
Yuav ua li cas hauv kev tshawb fawb preclinical?
Nyob rau hauv kev tshawb fawb preclinical, cov kws tshawb fawb sim lawv cov tswv yim rau cov tswv yim tshiab kev tiv thaiv biomedical hauv kev sim sim lossis hauv tsiajkev tshawb fawb soj ntsuam (saib hauv qab) hais txog kev tshawb fawb hauv tib neeg. Preclinical kev tshawb fawb suav nrog txhua yam uas tshwm sim ua ntej tus neeg sib tw raug txiav txim siab rau kev sim tib neeg.
txhais li cas los ntawm kev tshawb fawb preclinical?
Mloog cov lus. (pree-KLIH-nih-kul STUH-dee) Kev tshawb fawb siv tsiaj kom paub seb puas muaj tshuaj, txheej txheem, lossis kev kho mob zoo li yuav muaj txiaj ntsig. Cov kev tshawb fawb ua ntej yuav tshwm sim ua ntej kev sim hauv tib neeg ua tiav.
Qhov txawv ntawm qhov kev sim ua ntej thiab kev kuaj mob yog dab tsi?
Thaum kev tshawb fawb ua ntej teb cov lus nug tseem ceeb txog tshuaj muaj kev nyab xeeb, nws tsis yog qhov hloov pauv rau cov kev tshawb fawb txog cov tshuaj yuav cuam tshuam nrog tib neeg lub cev. "Kev tshawb fawb soj ntsuam" yog hais txog kev tshawb fawb, lossis kev sim, uas ua rau tib neeg.
Yuav ua li cas yog hom kev kawm preclinical?
Ntawm no peb sau cov kev tshawb fawb no thiab lawv qhov tseem ceeb hauv kev tshawb fawb ua ntej:
- ntsuas ntsuas. …
- Kev sim ntawm cov kab mob sib cais thiab kab mob kab mob. …
- Tests on animal model. …
- Kev soj ntsuam dav dav. …
- Kev kuaj pom tseeb thiab ua haujlwm zoo sib xws. …
- Mechanism of action. …
- Systemic pharmacology. …
- Quantitative test.
