Nyob rau sab sauv lagging strand, synthesis yog discontinuous, vim tshiab RNA primers RNA primers Ib primer muaj 20-30% hluavtaws cob, 60-80% hnyav thiab 2-5% additive agentQee cov primer muaj polyethylene (yas), kom zoo dua qub. https://en.wikipedia.org › wiki › Primer_(paint)
Primer (xim) - Wikipedia
yuav tsum tau muab ntxiv raws li qhib qhov kev sib txuas ntawm rab rawg replication diav rawg Qhov kev sib hloov diav rawg yog tus qauv uas tsim nyob rau hauv lub helical DNA ntev thaum DNA replicationNws yog tsim los ntawm helicases, uas tawg. cov hydrogen bonds tuav ob DNA strands ua ke nyob rau hauv lub helix. Cov qauv tsim muaj ob ceg "prongs", txhua tus ua los ntawm ib txoj hlua ntawm DNA.https://en.wikipedia.org › wiki › DNA_replication
DNA replication - Wikipedia
txuas ntxiv nthuav tawm cov qauv tshiab. Qhov no ua rau cov khoom tawg ntawm Okazaki tawg.
Vim li cas Okazaki fragments piav qhia lub tswvyim ntawm kev sib txuas tsis tu ncua?
Discontinuous Replication Generates Okazaki Fragments
Vim DNA polymerases tsis tuaj yeem pib DNA synthesis, txhua Okazaki fragment yog primed nrog luv RNA … Rau qee cov kab mob xws li Escherichia coli thiab bacteriophage T4, tib DNA polymerase yog lub luag haujlwm rau ob qho tib si ua thiab lagging strand DNA replication.
Puas Okazaki fragments txuas ntxiv lossis tsis txuas ntxiv?
Okazaki fragments yog luv luv ntawm DNA nucleotides (kwv yees li 150 txog 200 lub hauv paus khub ntev hauv eukaryotes) uas yog synthesized discontinuously thiab tom qab txuas ua ke los ntawm enzyme DNA ligase los tsim cov lagging strand thaum lub sij hawm DNA replication.
Vim li cas DNA rov ua txuas ntxiv thiab tsis txuas ntxiv?
Kev piav qhia: Hauv DNA ib txoj hlua yog nyob rau hauv 5' mus rau 3' kev taw qhia thiab lwm txoj hlua yog nyob rau hauv 3' mus rau 5' kev taw qhia. Lub DNA polymerase synthesize tus tshiab strand nyob rau hauv 5 'mus rau 3' kev taw qhiayog li ib strand yog synthesized tsis tu ncua thiab lwm yam discontinuously.
Vim li cas cov hlua tsis txuas ntxiv?
Vim qhov kev txwv kev ua haujlwm ntawm DNA polymerase tsis tuaj yeem ua cov saw hlau hauv 3 ' txog 5' kev taw qhia, ntawm cov hlua khi, kev sib txuas ntawm cov saw hlau yog tsis tu ncua ntawm 5' mus rau 3' kev taw qhia.
