Cov nucleosome core particle sawv cev rau thawj theem ntawm chromatin lub koom haum thiab yog tsim los ntawm ob daim ntawv theej ntawm txhua tus histones H2A, H2B, H3 thiab H4, sib sau ua ke hauv cov tub ntxhais octameric nrog 146-147 bp ntawm DNA nruj nreem qhwv ib ncig ntawm nws [1, 2].
Tus qauv ntawm histones yog dab tsi?
Txhua histone octamer yog tsim los ntawm ob daim ntawv theej ntawm txhua tus histone proteins H2A, H2B, H3, thiab H4 Cov saw hlau ntawm nucleosomes ces qhwv rau hauv 30 nm kauv hu ua a solenoid, qhov twg ntxiv H1 histone proteins yog txuam nrog txhua nucleosome kom tswj cov qauv chromosome.
Histones yog dab tsi thiab lawv nyob li cas hauv nucleosomes?
Histones muaj ntau qhov zoo ntawm cov amino acids xws li lysine thiab arginine. Yog li, lawv tuaj yeem khi electrostatically rau qhov tsis zoo phosphate pawg ntawm nucleotides. Nucleosomes yog tsim los ntawm tag nrho cov histones tshwj tsis yog H1 …
Puas yog histone octamer ib lub qauv quaternary?
Cov tub ntxhais nucleosome feem ntau muaj nyob ib ncig ntawm 146 DNA puag khub qhwv ib ncig ntawm histone octamer. Lub histone octamer yog tsim los ntawm yim tag nrho histone proteins, ob ntawm txhua yam ntawm cov proteins hauv qab no: H2A, H2B, H3, thiab H4. … Kev hloov kho rau cov proteins histone thiab lawv cov DNA raug cais raws li quaternary qauv
Tus qauv ntawm histone protein yog dab tsi?
Histone Protein Structure. Histones yog cov txheej txheem tseem ceeb ntawm cov chromosomes. Lub DNA molecule yog qhwv ob zaug ib ncig ntawm Histone Octamer los ua Nucleosome. Rau Nucleosomes tau sib sau ua ke rau hauv Solenoid hauv kev koom nrog H1 histones.
