[ah-me″no-kwin´o-lēn] a heterocyclic compound derived los ntawm quinoline los ntawm kev sib ntxiv ntawm ib pawg amino; 4-aminoquinoline thiab 8-aminoquinoline derivatives yog pab pawg ntawm cov tshuaj tiv thaiv kab mob.
aminoquinoline yog dab tsi?
Aminoquinolines yog derivatives ntawm quinoline, tseem ceeb tshaj plaws rau lawv lub luag haujlwm ua tshuaj tiv thaiv kab mob. Nyob ntawm qhov chaw ntawm cov amino pawg, lawv tuaj yeem muab faib ua: 4-Aminoquinoline.
Vim li cas quinine yog 4-Aminoquinoline muab laj thawj?
4-Aminoquinoline yog ib hom aminoquinoline nrog cov amino pawg ntawm 4-txoj hauj lwm ntawm quinoline. Lub compound muaj tau siv los ua tus thawj coj rau kev sib txuas ntawm nws cov derivatives Ntau yam derivatives ntawm 4-aminoquinoline yog cov tshuaj tiv thaiv kab mob muaj txiaj ntsig zoo hauv kev kho cov kab mob erythrocytic plasmodial.
Qhov twg ntawm cov tshuaj tiv thaiv kab mob hauv qab no muaj nyob rau 8 Aminoquinoline derivatives?
Cov tshuaj tiv thaiv kab mob primaquine, ib qho 8-aminoquinoline derivative, yog ib qho piv txwv ntawm cov tshuaj zoo li no.
YPuas yog chloroquine yog 4-Aminoquinoline?
Chloroquine (CQ) yog kev nyab xeeb thiab kev lag luam 4-aminoquinoline (AQ) tshuaj tiv thaiv kab mob. Txawm li cas los xij, nws tus nqi tau raug cuam tshuam loj heev los ntawm kev nce ntxiv ntawm CQ tsis kam. Txoj kev tshawb no tau tshuaj xyuas 108 AQs, suav nrog 68 cov khoom sib xyaw ua ke tshiab.
