thawj genetic engineered, hluavtaws "tib neeg" insulin yog tsim nyob rau hauv 1978 siv cov kab mob E. coli los tsim cov tshuaj insulin. Eli Lilly tau mus rau xyoo 1982 los muag thawj cov khoom lag luam biosynthetic tib neeg insulin raws li lub npe humulin.
Leej twg xub tsim cov tshuaj insulin?
Frederick Banting thiab Charles Best Lawv nrhiav tau tshaj tawm rau lub ntiaj teb thaum lub Kaum Ib Hlis 14, 1921. Ob hlis tom qab, nrog kev txhawb nqa ntawm J. J. R. MacLeod ntawm University of Toronto, ob tus kws tshawb fawb tau pib npaj rau kev kho tshuaj insulin ntawm tib neeg.
insulin ua li cas xyoo 1970?
Recombinant DNA, cov txheej txheem lab tsim nyob rau xyoo 1970s thaum ntxov, tso cai rau cov tuam txhab tshuaj los tsim cov kab mob genetic engineers los tsim tib neeg cov tshuaj insulin. Qhov no "recombinant insulin" thawj zaug tuaj ntawm kev lag luam hauv nruab nrab-1980s, nyob rau hauv lub npe humulin.
Cov neeg mob ntshav qab zib tau nyob ntev npaum li cas ua ntej insulin?
Ua ntej nrhiav pom cov tshuaj insulin, cov ntshav qab zib tau poob. Txawm noj zaub mov nruj los lawv yuav kav ntev tsis ntau tshaj peb lossis plaub xyoos.
Tus neeg mob ntshav qab zib puas muaj sia nyob yam tsis muaj insulin?
Yog tsis muaj tshuaj insulin, cov neeg mob ntshav qab zib hom 1 raug mob hu ua Diabetic Ketoacidosis (DKA) Yog tias tsis kho, tib neeg tuag sai thiab feem ntau ib leeg. Qhov kev poob siab ntawm lub neej los ntawm DKA tuaj yeem tiv thaiv. Yog tias cov tshuaj insulin tau nkag mus tau yooj yim thiab pheej yig, txoj sia yuav cawm tau.
