Phosphorylation tuaj yeem tshwm sim ntawm serine, threonine thiab tyrosine sab chains (feem ntau hu ua 'residues') los ntawm phosphoester bond tsim, ntawm histidine, lysine thiab arginine los ntawm phosphoramidate phosphoramidate A (phosphorodiamidate). los yog diamidophosphate) yog ib qho phosphate uas muaj ob pawg OH hloov los ntawm NR2 pawg los muab ib hom nrog cov qauv dav dav O=P(OH)(NH 2)2 Kev hloov ntawm tag nrho peb pawg OH muab cov phosphoric triamides (O=P(NR2)3), uas feem ntau hu ua phosphoramides. https://en.wikipedia.org › wiki › Phosphoramidate
YPhosphoramidate - Wikipedia
bonds, thiab ntawm aspartic acid thiab glutamic acid los ntawm kev sib xyaw anhydride linkages.
Cov amino acids twg tuaj yeem ua phosphorylated thiab yog vim li cas?
Phosphorylation feem ntau pom ntawm qhov tshwj xeeb serine thiab threonine amino acid residues hauv cov protein, tab sis nws kuj tshwm sim ntawm tyrosine thiab lwm cov amino acid residues (histidine, aspartic acid, glutamic acid.) thiab.
Dab tsi 3 amino acids yog phosphorylated?
Cov amino acids feem ntau phosphorylated yog serine, threonine, tyrosine hauv eukaryotes, thiab tseem histidine hauv prokaryotes thiab nroj tsuag (txawm tias tam sim no paub tias muaj ntau nyob rau hauv tib neeg). Cov phosphorylations ua lub luag haujlwm tseem ceeb thiab muaj txiaj ntsig zoo hauv kev taw qhia txoj hauv kev thiab cov metabolism.
Yuav ua li cas residues yuav phosphorylated hauv eukaryotes?
Phosphorylation zoo li tseem ceeb dua thiab nthuav dav hauv cov hlwb eukaryotic, tab sis thaum histidine phosphorylation tshwm sim tsawg kawg ib co eukaryotes, feem ntau eukaryotic protein phosphorylation tshwm sim ntawm serine, threonine, thiab tyrosine residues (Manning et al., 2002a).
Qhov twg ntawm cov seem hauv qab no tuaj yeem dhau los ua phosphorylated hauv cov protein?
Proteins tuaj yeem ua phosphorylated ntawm serine, threonine lossis tyrosine residues. Feem ntau phosphorylation tshwm sim ntawm serine thiab threonine (saib Ch. 25), nrog tsawg dua 1% ntawm tyrosine.
